Cialis is an ED drug that acts as a vasodilator. It increases blood circulation and volume in the genital region by blocking the POE-5 enzyme, which is responsible for preventing erection or making it difficult to maintain. As a matter of fact, alcohol exhibits a similar vasodilating effect on most individuals. Thus, interactions between both is mostly dependent on the quantity of consumed alcohol. When consumed in small amounts, alcohol does not usually negatively impact the effects of Cialis. Thus, when taken in moderation, it is possible to use both substances simultaneously in a safe and sexually satisfying way. However, it should be noted that doctors discourage users from mixing Cialis with alcohol.

Interaction with high doses of alcohol

Cialis and AlcoholExcessive alcohol consumption can have significantly adverse effects. Consumption of alcohol in large quantities is quite dangerous by itself. And like most medicines, Cialis must not be taken together with large amounts of alcohol. There are two main reasons for this.

The first one is that excessive consumption of alcohol will by itself decrease your level of libido. Alcohol in large quantities causes numbness and impairs sensitivity, thus reducing response to sexual stimuli. Another issue is dehydration: water loss in the body spurs the release of the hormone angiotensin (vasoconstrictor), which is associated with erectile dysfunction. Alcohol also directs blood to the liver so that it is metabolized by the body. Consequently, less blood is available for an erection, which can inhibit the drug from producing its desired effect.

The second reason is that Cialis, especially when combined with alcohol, can cause dizziness, nausea, vomiting, tachycardia and, most seriously of all, a sudden drop in blood pressure that may even lead to fainting. The blood pressure drop occurs because both ethanol and Cialis cause blood vessels to dilate. Vasodilation is a natural body process that can be catalyzed by drugs, but it can be dangerous when it happens very quickly, even without medications. The fact that both ethanol and Cialis are metabolized by the liver makes the interaction even more dangerous, since possible side effects become more likely (alcohol and Cialis have relatively similar side effects).

Small amounts of alcohol

Moderate alcohol consumption should not be reason for concern. But given that both substances can lower blood pressure, the safest approach is to limit alcohol intake to a minimum while using the ED drug in order to avoid such side effects as dizziness or heart palpitations.